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In this video, we will take a look at the most common causes of grey hair.
Premature greying of hair, also known as canities, can have negative effects on appearance,
confidence, self-esteem, and social acceptance of the affected individual
Hair pigmentation is one of the most unique features in humans ranging from black, brown, and
blonde to red.
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The colour of human hair is due to the pigment “melanin” produced by melanocytes,
the same cells which are responsible for the pigmentation of our skin. There are two main forms of
hair pigment. There’s eumelanin and pheomelanin. Eumelanin is what we see in brunettes and
darker-haired people, and pheomelanin is what we see in blonds and redheads.
These Melanocytes are located in the hair follicle which is basically from where the root of the hair
originates. Each hair grows from a single Hair follicle.
As the strand of the hair grows, melanocytes inject the pigment (melanin) into cells containing
keratin.
Keratin is the protein that makes up our hair, skin, and nails. Throughout the years,
melanocytes continue to inject pigment into the hair’s keratin, giving it a colorful hue.
With age comes a reduction of melanin. The hair turns grey and eventually white, and this is a
natural process. But the problem arises when this reduction in the production of melanin comes
early in age due to some other reasons and there are plenty of reasons due to which this can occur.
Let’s look at some of the most common reasons for premature greying of hair.
#ANTIAGING #HAIR #SKINCARE #DRDRAY
TODAY I TALK ABOUT GRAY HAIR AND GOING GRAY EARLY.
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💜REFERENCES
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Panhard S, Lozano I, Loussouarn G. Greying of the human hair: A worldwide survey, revisiting the ‘50’ rule of thumb. Br J Dermatol. 2012;167:865–73.
Ito S, Wakamatsu K. Diversity of human hair pigmentation as studied by chemical analysis of eumelanin and pheomelanin. J Eur Acad Dermatol Venereol. 2011;25:1369–80.
Rees J. Plenty new under the sun. J Invest Dermatol. 2006;126:1691–2.
Slominski A, Wortsman J, Plonka PM, Schallreuter KU, Paus R, Tobin DJ. Hair follicle pigmentation. J Invest Dermatol. 2005;124:13–21.
Peters EM, Imfeld D, Gräub R. Graying of the human hair follicle. J Cosmet Sci. 2011;62:121–5.
Arck PC, Overall R, Spatz K, Liezman C, Handjiski B, Klapp BF, et al. Towards a “free radical theory of graying”: Melanocyte apoptosis in the aging human hair follicle is an indicator of oxidative stress induced tissue damage. FASEB J. 2006;20:1567–9.
Choi HI, Choi GI, Kim EK, Choi YJ, Sohn KC, Lee Y, et al. Hair greying is associated with active hair growth. Br J Dermatol. 2011;165:1183–9.
Goodier M, Hordinsky M. Normal and aging hair biology and structure ‘aging and hair’ Curr Probl Dermatol. 2015;47:1–9.
Daulatabad D, Singal A, Grover C, Chhillar N. Profile of Indian patients with premature canities. Indian J Dermatol Venereol Leprol. 2016;82:169–72.
Trüeb RM. Oxidative stress in ageing of hair. Int J Trichology. 2009;1:6–14.
Wood JM, Decker H, Hartmann H, Chavan B, Rokos H, Spencer JD, et al. Senile hair graying: H2O2-mediated oxidative stress affects human hair color by blunting methionine sulfoxide repair. FASEB J. 2009;23:2065–75.
Irie M, Asami S, Nagata S, Miyata M, Kasai H. Relationships between perceived workload, stress and oxidative DNA damage. Int Arch Occup Environ Health. 2001;74:153–7.
Akin Belli A, Etgu F, Ozbas Gok S, Kara B, Dogan G. Risk factors for premature hair graying in young Turkish adults. Pediatr Dermatol. 2016;33:438–42.
Daulatabad D, Singal A, Grover C, Sharma SB, Chhillar N. Assessment of oxidative stress in patients with premature canities. Int J Trichology. 2015;7:91–4.
Shi Y, Luo LF, Liu XM, Zhou Q, Xu SZ, Lei TC. Premature graying as a consequence of compromised antioxidant activity in hair bulb melanocytes and their precursors. PLoS One. 2014;9:e93589.
Jimbow K, Chen H, Park JS, Thomas PD. Increased sensitivity of melanocytes to oxidative stress and abnormal expression of tyrosinase-related protein in vitiligo. Br J Dermatol. 2001;144:55–65
Dawber RP. Integumentary associations of pernicious anaemia. Br J Dermatol. 1970;82:221–3.
van Beek N, Bodó E, Kromminga A, Gáspár E, Meyer K, Zmijewski MA, et al. Thyroid hormones directly alter human hair follicle functions: Anagen prolongation and stimulation of both hair matrix keratinocyte proliferation and hair pigmentation. J Clin Endocrinol Metab. 2008;93:4381–8.
Hartmann JT, Kanz L. Sunitinib and periodic hair depigmentation due to temporary c-KIT inhibition. Arch Dermatol. 2008;144:1525–6.
Sideras K, Menefee ME, Burton JK, Erlichman C, Bible KC, Ivy SP. Profound hair and skin hypopigmentation in an African American woman treated with the multi-targeted tyrosine kinase inhibitor pazopanib. J Clin Oncol. 2010;28:e312–3.
Etienne G, Cony-Makhoul P, Mahon FX. Imatinib mesylate and gray hair. N Engl J Med. 2002;347:446.
Jo SJ, Paik SH, Choi JW, Lee JH, Cho S, Kim KH, et al. Hair graying pattern depends on gender, onset age and smoking habits. Acta Derm Venereol. 2012;92:160–1.
Mosley JG, Gibbs AC. Premature grey hair and hair loss among smokers: A new opportunity for health education? BMJ. 1996;313:1616.
Zayed AA, Shahait AD, Ayoub MN, Yousef AM. Smokers’ hair: Does smoking cause premature hair graying? Indian Dermatol Online J. 2013;4:90–2.
Trüeb RM. Association between smoking and hair loss: Another opportunity for health education against smoking? Dermatology. 2003;206:189–91.
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Disclaimer: This video is not intended to provide diagnosis, treatment or medical advice. Content provided on this Youtube channel is for informational purposes only. Please consult with a physician or other healthcare professional regarding any medical or health related diagnosis or treatment options. Information on this Youtube channel should not be considered as a substitute for advice from a healthcare professional. The statements made about specific products throughout this video are not to diagnose, treat, cure or prevent disease. Video Rating: / 5
Scientists say they may have found a cure for gray hair. Erin Burnett reports in tonight’s OutTake. For more CNN videos, visit our site at http://www.cnn.com/video/ Video Rating: / 5
Home Remedies For White Hair or premature Grey Hair which is made of all natural products which are known as one of the best products for hair care in our Ayurveda as well.
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Why is it so hard to find a treatment for hair loss? Every year people spend billions trying to prevent hair loss. So why haven’t we found a cure for going bald? Science writer Stephen Buranyi explains hair loss.
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