What is sickle cell anemia? Sickle cell anemia is an autosomal recessive genetic condition where the beta-globin protein subunit of hemoglobin is misshapen, which ultimately leads to a sickle-shaped red blood cell, which is prematurely destroyed and can get stuck in small blood vessels. Find our full video library only on Osmosis: http://osms.it/more.
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In this video I have explained hemoglobin electrophoresis normal electrophoretic bands along with different hemoglobinopathies like sickle cell trait, sickle cell anemia, hemoglobin C trait, hemoglobin C disease, hemoglobin SC disease, beta-thalassemia minor and beta-thalassemia major.
Thanks to Rachael Daniela for helping me in recording this video!
Hemoglobin electrophoresis is a blood test that can detect different types of hemoglobin. It uses the principles of gel electrophoresis to separate out the various types of hemoglobin and is a type of native gel electrophoresis. The test can detect abnormal levels of HbS, the form associated with sickle-cell disease, as well as other abnormal hemoglobin-related blood disorders, such as alpha thalassaemia and hemoglobin C.
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HbE disease is one type of thalassemia, defect in haemoglobin molecule. HbE disaese is minor type of thassemia.
